Fig. 1 · Structure
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Uniconazole
Cytochrome P450 Inhibitor
Uniconazole, a selective inhibitor of cytochrome P450 enzymes, primarily targets ABA 8’-hydroxylase, exhibiting an IC50 of 68 nM. This compound serves as a competitive inhibitor of CYP707A3 with a Ki value of 8 nM. Uniconazole effectively inhibits gibberellin and, to a lesser extent, brassinosteroid biosynthesis, making it a valuable tool in studies of plant growth regulation and developmental processes. Its application extends to research exploring the modulation of plant hormones.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 83657-22-1 |
| Applications | Cytochrome P450 Inhibitor |
| Formula | C15H18ClN3O |
| Molecular Weight | 291.78 |
| SMILES | OC(C(C)(C)C)/C(N1N=CN=C1)=C\C2=CC=C(Cl)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.