UniPR1447 is a dual antagonist of EphA2 and EphB2, exhibiting an IC50 of 6.6 μM for the inhibition of the EphA2-ephrin-A1 interaction. This compound serves as a valuable tool in research focused on the role of Eph receptors in cellular processes such as angiogenesis, tumor progression, and neural development. Its application in studies targeting EphA2 and EphB2 signaling pathways contributes to understanding their implications in various diseases, making UniPR1447 a relevant reagent for therapeutic exploration.
UniPR1447 is a dual antagonist of EphA2 and EphB2, exhibiting an IC50 of 6.6 μM for the inhibition of the EphA2-ephrin-A1 interaction. This compound serves as a valuable tool in research focused on the role of Eph receptors in cellular processes such as angiogenesis, tumor progression, and neural development. Its application in studies targeting EphA2 and EphB2 signaling pathways contributes to understanding their implications in various diseases, making UniPR1447 a relevant reagent for therapeutic exploration.
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