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Biological Activity
UPF-648 is a potent kynurenine 3-monooxygenase (KMO) inhibitor; exhibits highly active at 1 uM (81 ?? 10% KMO inhibition); ineffective at blocking KAT activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 38.6 mL | 192.98 mL | 385.97 mL |
| 0.5 mM | 7.72 mL | 38.6 mL | 77.19 mL |
| 1 mM | 3.86 mL | 19.3 mL | 38.6 mL |
| 5 mM | 0.77 mL | 3.86 mL | 7.72 mL |
*The above data is based on the productmolecular weight 259.09. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21239 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 213400-34-1 |
| Formula | C11H8Cl2O3 |
| M. Wt | 259.09 |
| Purity | >98% |
| SMILES | O=C([C@@H]1[C@@H](C(C2=CC=C(Cl)C(Cl)=C2)=O)C1)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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