UPF-648 is a potent kynurenine 3-monooxygenase (KMO) inhibitor; exhibits highly active at 1 uM (81 ?? 10% KMO inhibition); ineffective at blocking KAT activity.
UPF-648 is a potent kynurenine 3-monooxygenase (KMO) inhibitor; exhibits highly active at 1 uM (81 ?? 10% KMO inhibition); ineffective at blocking KAT activity.
Product Information
Catalog Num
A21239
Formula
C11H8Cl2O3
Molecular Weight
259.09
CAS Number
213400-34-1
SMILES
O=C([C@@H]1[C@@H](C(C2=CC=C(Cl)C(Cl)=C2)=O)C1)O
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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