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UPG-111

UTR Negative Allosteric Regulator

UPG-111 is a peptide that functions as a negative allosteric regulator of the Urotensin II receptor (UTR). It effectively inhibits vasoconstriction caused by UTR agonists by decreasing both the peak response and agonist sensitivity. Notably, UPG-111 does not trigger calcium release or induce contraction in endothelium-deprived rat aortic rings. This compound is valuable for investigating diseases associated with the angiotensinergic system.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3090687-02-5
Applications	UTR Negative Allosteric Regulator
Formula	C₆₄H₈₇N₁₃O₁₇S₂
Molecular Weight	1374.58

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.