Fig. 1 · Structure

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UR-12947

GP IIb-IIIa Antagonist

UR-12947 is a glycoprotein IIb-IIIa antagonist that effectively inhibits platelet aggregation. Demonstrating a potent IC50 value of 3.5 nM in human platelet-rich plasma, UR-12947 serves as a valuable tool for studying arterial thrombotic diseases and related cardiovascular research. Its specific action on GP IIb-IIIa allows for detailed investigations into platelet-mediated processes and their role in thrombus formation.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 718595-27-8
Applications GP IIb-IIIa Antagonist
Formula C26H37N5O5S2
Molecular Weight 563.73
SMILES
O=S(N[C@H](C(O)=O)CNC(C1=C(C(C)C)N=C(N2CCC(C3CCNCC3)CC2)S1)=O)(C4=CC=CC=C4)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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