Fig. 1 · Structure
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UR-7247
Angiotensin II AT1 Antagonist
UR-7247 is a potent, orally bioavailable antagonist of the angiotensin II AT1 receptor. It exhibits significant biological activity by lowering arterial pressure and enhancing renal blood flow. This compound is useful in the investigation of cardiovascular and renal function, particularly in studies focused on hypertension and related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 177847-28-8 |
| Applications | Angiotensin II AT1 Antagonist |
| Formula | C24H26N6O2 |
| Molecular Weight | 430.50 |
| SMILES | O=C(O)C1=C(N(N=C1C(C)C)CCC)CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=NN4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.