Fig. 1 · Structure
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Urolithin D
EphA Receptor Antagonist
Urolithin D is a selective antagonist of the EphA receptor, specifically inhibiting EphA2-ephrin-A1 binding with an IC50 of 0.9 μM. This compound exhibits significant antioxidant activity by scavenging free radicals and repairing oxidized DNA damage. Furthermore, Urolithin D promotes fatty acid oxidation and suppresses triglyceride accumulation through activation of the AMPK signaling pathway. It is a valuable reagent for research in tumor biology, metabolic disorders, and inflammatory conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 131086-98-1 |
| Applications | EphA Receptor Antagonist |
| Formula | C13H8O6 |
| Molecular Weight | 260.20 |
| Synonyms | 3,4,8,9-Tetrahydroxy urolithin |
| SMILES | O=C1C2=CC(O)=C(O)C=C2C3=CC=C(O)C(O)=C3O1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.