Fig. 1 · Structure

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USP1-IN-3

USP1 Inhibitor

USP1-IN-3 is a selective inhibitor of USP1, targeting the USP1-UAF1 complex with an IC50 value of less than 30 nM. This compound is valuable for investigating the role of USP1 in cancer biology, providing a tool for studying its involvement in tumorigenesis and potential therapeutic applications. Research utilizing USP1-IN-3 can contribute to understanding the mechanisms behind cancer progression and the development of novel treatment strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2821749-58-8
Applications USP1 Inhibitor
Formula C27H24F3N7O
Molecular Weight 519.52
SMILES
COC1=C(C2=NC3=C(N(C)C=C3CC4=CC=C(C5=NC(C(F)(F)F)=CN5C)C=C4)C=N2)C(C6CC6)=NC=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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