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Utomilumab
Utomilumab (PF 05082566) is a fully human IgG2 agonist monoclonal antibody designed for selective binding to 4-1BB/CD137, a costimulatory receptor involved in the regulation of immune cell activation and survival. This antibody has potential applications in oncology research, particularly in the study of follicular and other CD20+ non-Hodgkin lymphomas, where it may enhance antitumor immune responses.
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Biological Activity
Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1417318-27-4 |
| Molecular Weight | 142780 |
| Synonyms | PF 05082566 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.