Fig. 1 · Structure
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Val-Cit-amide-Cbz-N(Me)-Maytansine
ADC Antibody
Val-Cit-amide-Cbz-N(Me)-Maytansine is a targeted antibody-drug conjugate (ADC) designed to specifically bind to the hepatocyte growth factor receptor c-Met (MET). This compound exhibits potent cytotoxicity, making it suitable for research applications in cancer immunotherapy. Its unique structure enhances the selective delivery of cytotoxic agents to MET-expressing tumors, facilitating studies in targeted therapy and drug delivery systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1628543-59-8 |
| Applications | ADC Antibody |
| Formula | C55H78ClN9O15 |
| Molecular Weight | 1140.71 |
| SMILES | O=C(N(C)[C@@H](C)C(O[C@H]([C@@]1(C)[C@@H](O1)[C@@H]2C)CC(N(C)C3=C(Cl)C(OC)=CC(C/C(C)=C/C=C/[C@@H](OC)[C@]4(O)NC(O[C@H]2C4)=O)=C3)=O)=O)CCN(C)C(OCC5=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)N)=O)=O)C=C5)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.