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Val-Cit-PAB-DEA-Duo-DM

Drug-Linker Conjugate

Val-Cit-PAB-DEA-Duo-DM is a specialized drug-linker conjugate designed for antibody-drug conjugate (ADC) synthesis. Comprising the Val-Cit-PAB linker, the DEA spacer, and the Duocarmycin DM toxin, this reagent facilitates the targeted delivery of cytotoxic agents to malignant cells. Its key applications include the development of ADCs for cancer research, enhancing therapeutic efficacy while minimizing off-target effects.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1698870-53-9
Applications	Drug-Linker Conjugate
Formula	C₅₀H₆₃ClN₁₀O₉
Molecular Weight	983.55
SMILES	ClC[C@H]1C2=C(C=C(C3=CC=CC=C32)OC(N(C)CCN(C)C(OCC4=CC=C(C=C4)NC([C@H](CCCNC(N)=O)NC([C@@H](N)C(C)C)=O)=O)=O)=O)N(C1)C(C5=CC6=CC(OCCN(C)C)=CC=C6N5)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.