Fig. 1 · Structure
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Valanafusp alfa
Anti-HIR IDUA-Fusion mAb
Valanafusp alfa is a chimeric monoclonal antibody that combines human α-L-iduronidase (IDUA) with targeting capabilities for the human insulin receptor (HIR). This reagent demonstrates brain-penetrating properties, making it a valuable tool for research on mucopolysaccharidosis type I (MPS I) and related therapeutic investigations. Its unique mechanism allows for the exploration of potential treatment strategies for lysosomal storage disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1815583-32-4 |
| Applications | Anti-HIR IDUA-Fusion mAb |
| Molecular Weight | 284.23 kDa |
| Synonyms | AGT-181; HIRMAb-IDUA |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.