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VARS1-IN-2

VARS1 Inhibitor

VARS1-IN-2 is a selective inhibitor of VARS1, exhibiting a Kd of 0.014 µM. This compound effectively interferes with VARS1's tRNA aminoacylation activity, demonstrating significant anti-prostate cancer effects without altering VARS1 expression at either the mRNA or protein level. VARS1-IN-2 is valuable for research focused on understanding the role of tRNA aminoacylation in cancer biology and related therapeutic applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	667914-07-0
Applications	VARS1 Inhibitor
Formula	C₂₆H₁₇N₃O₂S₂
Molecular Weight	467.56
SMILES	O=C(NC1=C/2C=CC=C1)C2=C3C(N4C(S\3)=NC5=C(CCC6=C5C=CC=C6)C4C7=CC=CS7)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.