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Vasoactive intestinal contractor

Catalog No.: A38509
vasoactive peptide
Vasoactive intestinal contractor is a vasoactive peptide that functions as a potent stimulator of intracellular calcium concentration. It activates calcium signaling pathways, leading to a rapid increase in Ca2+ levels in cells such as fura-2-overexpressed Swiss 3T3 fibroblasts. This compound is utilized in research related to cellular signaling, smooth muscle contraction, and studies on the endothelin family of peptides.
Vasoactive intestinal contractor 138863-63-5 vasoactive peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionVasoactive intestinal contractor is a vasoactive peptide that functions as a potent stimulator of intracellular calcium concentration. It activates calcium signaling pathways, leading to a rapid increase in Ca2+ levels in cells such as fura-2-overexpressed Swiss 3T3 fibroblasts. This compound is utilized in research related to cellular signaling, smooth muscle contraction, and studies on the endothelin family of peptides.
Product Information
Catalog NumA38509
FormulaC116H161N27O32S4
Molecular Weight2573.94
CAS Number138863-63-5
SequenceCys-Ser-Cys-Asn-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridge: Cys1-Cys15, Cys3-Cys11)
Sequence shorteningCSCNSWLDKECVYFCHLDIIW (Disulfide bridge: Cys1-Cys15, Cys3-Cys11)
SMILESC(C=1C=2C(NC1)=CC=CC2)[C@H]3C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@]4(CSSC[C@@](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N3)(NC(=O)[C@H](CO)NC(=O)[C@@H](N)CSSC[C@@H](C(N[C@@H](CC5=CN=CN5)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC=6C=7C(NC6)=CC=CC7)C(O)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CC(O)=O)=O)CC(C)C)=O)=O)NC(=O)[C@H](CC8=CC=CC=C8)NC(=O)[C@H](CC9=CC=C(O)C=C9)NC(=O)[C@H]([C@@H](C)C)NC4=O)[H])[H]
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