Fig. 1 · Structure
Documents & Downloads
VAV1 degrader-2
VAV 1 Molecular Glue Degrader
VAV1 degrader-2 is a molecular glue degrader targeting VAV1 with a DC50 of 4.41 nM. This compound facilitates the degradation of VAV1, leading to modulation of key signaling pathways involved in inflammatory and autoimmune diseases. VAV1 degrader-2 is suitable for research applications aiming to elucidate the role of VAV1 in disease mechanisms and therapeutic interventions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 3050683-29-6 |
| Applications | VAV 1 Molecular Glue Degrader |
| Formula | C22H20ClN3O2 |
| Molecular Weight | 393.87 |
| SMILES | ClC1=C(C2CCC(NC2=O)=O)C=CC=C1C3=CC=C(CC4=NN(C)C=C4)C=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.