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vc-PAB-DMEA-PNU159682

ADC

vc-PAB-DMEA-PNU159682 is a sulfomaleimide-based linker designed for use in antibody-drug conjugate (ADC) synthesis. This compound exhibits excellent serum stability, making it suitable for applications requiring prolonged circulation in biological systems. Its structural properties facilitate efficient conjugation to antibodies, enhancing the pharmacological efficacy of the resulting ADCs in targeted cancer therapies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2227350-96-9
Applications	ADC
Formula	C₅₆H₇₂N₈O₁₉
Molecular Weight	1161.21
SMILES	OC1=C2C(C(C3=C(OC)C=CC=C3C2=O)=O)=C(O)C([C@H]4O[C@H]5C[C@]6([H])N7[C@]([C@H](OCC7)OC)([H])O[C@]6([H])[C@@H](O5)C)=C1C[C@](O)(C4)C(COC(N(C)CCN(C)C(OCC8=CC=C(C=C8)NC([C@H](CCCNC(N)=O)NC([C@@H](N)C(C)C)=O)=O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.