Fig. 1 · Structure
Documents & Downloads
Vemurafenib-d7
Stable Isotope
Vemurafenib-d7 is a deuterium-labeled derivative of Vemurafenib, a selective and potent inhibitor of B-RAF kinase, demonstrating IC50 values of 31 nM for RAFV600E and 48 nM for c-RAF-1. This compound is instrumental in studying the pharmacokinetics and metabolism of Vemurafenib in biological systems. Additionally, it is useful in research applications involving cell autophagy and targeted cancer therapies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1365986-73-7 |
| Applications | Stable Isotope |
| Formula | C23H11D7ClF2N3O3S |
| Molecular Weight | 496.97 |
| Synonyms | PLX4032-d7; RG7204-d7; RO5185426-d7 |
| SMILES | O=C(C1=C(C(NS(C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])(=O)=O)=CC=C1F)F)C2=CNC3=NC=C(C4=CC=C(C=C4)Cl)C=C23 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.