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Vepsitamab
Vepsitamab (AMG 199) is a bispecific T-cell engager (BiTE) antibody designed for precise dual targeting of CD3 on T cells and MUC17 on tumor cells. This antibody facilitates the redirection of T cell cytotoxic activity towards MUC17-expressing tumor cells, resulting in targeted tumor cell lysis. Additionally, Vepsitamab promotes T cell activation and proliferation, enhancing anti-tumor immune responses. This product is pivotal for research focused on cancer immunotherapy and the molecular mechanisms of T cell-mediated cytotoxicity.
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Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2413453-53-7 |
| Synonyms | AMG 199 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.