Fig. 1 · Structure
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Veratridine
VGSCs Agonist
Veratridine is a potent agonist of voltage-gated sodium channels (VGSCs). This plant-derived neurotoxin enhances sodium ion permeability by preventing channel inactivation, thereby inducing prolonged sodium ion flow across the membrane. Veratridine is particularly effective on the Nav1.7 channel, exhibiting an IC50 of 18.39 µM, making it useful for research studies focused on ion channel modulation and neurophysiology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 71-62-5 |
| Applications | VGSCs Agonist |
| Formula | C36H51NO11 |
| Molecular Weight | 673.79 |
| Synonyms | 3-Veratroylveracevine |
| SMILES | C[C@@]12[C@]34[C@](CC[C@]1([H])[C@@](O)([C@@H](OC(C5=CC(OC)=C(OC)C=C5)=O)CC2)O4)([H])[C@@]6(O)[C@](O)([C@@]7([H])[C@@](O)([C@](O)([C@@]8([H])N(C[C@@H](C)CC8)C7)C)[C@@H](O)C6)C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.