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Biological Activity
Verucerfont, also known as GSK561679 and NBI77860, is a CRF-1 antagonist. Verucerfont blocks the CRH-1 receptor, and so reduces ACTH release following chronic stress.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.6 mL | 123 mL | 246.01 mL |
| 0.5 mM | 4.92 mL | 24.6 mL | 49.2 mL |
| 1 mM | 2.46 mL | 12.3 mL | 24.6 mL |
| 5 mM | 0.49 mL | 2.46 mL | 4.92 mL |
*The above data is based on the productmolecular weight 406.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16950 |
|---|---|
| Actions | Antagonist |
| CAS No. | 885220-61-1 |
| Formula | C22H26N6O2 |
| M. Wt | 406.49 |
| Purity | >98% |
| Synonyms | GSK561679, GSK-561679, GSK 561679, SK-561,679, GSK561679A, NBI77860, NBI-77860, NBI 77860 |
| SMILES | CC[C@H](NC1=CC(C)=NC2=C(C3=CC=C(OC)C=C3C)C(C)=NN12)C4=NC(C)=NO4 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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