Documents & Downloads

Vesencumab

Vesencumab (MNRP-1685A) is an IgG1 monoclonal antibody that targets neuropilin-1 (NRP-1), a co-receptor involved in angiogenesis and the enhancement of vascular endothelial growth factor (VEGF) signaling through its association with VEGFR-2. By binding to NRP-1, Vesencumab effectively inhibits the interaction between NRP-1 and VEGFR-2, thereby exerting anti-angiogenic and anti-neoplastic effects. This antibody is particularly useful in research focused on the mechanisms of metastasis and tumor growth in solid tumors, including studies on ovarian cancer.

In Stock

Biological Activity

Target & Activity

neuropilin-1

Product Details

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 1205533-60-3
Molecular Weight 145262
Synonyms MNRP-1685A

Storage

Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Customer Questions
Biosimilar antibodies are research-grade recombinant antibodies designed to closely resemble approved therapeutic antibodies in terms of amino acid sequence, structural characteristics, and biological activity. These antibodies are generated using recombinant expression technologies and retain the same variable regions as their corresponding reference therapeutics, thereby preserving target specificity and binding affinity. Owing to these properties, biosimilar antibodies serve as reliable and cost-effective research reagents for applications in drug discovery, pharmacological studies, and basic biomedical research. Research-grade biosimilar antibodies have been successfully expressed and functionally validated against a wide range of widely studied targets. These antibodies can be directly utilized as positive control reagents in drug discovery programs, as well as reference tools for rapid verification of the biological functions of target proteins in biochemical and cellular assays.
Loading...

Added to your cart

View Cart Checkout
Loading...