Fig. 1 · Structure
Documents & Downloads
VH032 amide-PEG1-acid
VHL-1 alkyl Linker
VH032 amide-PEG1-acid is a VHL-1 alkyl linker designed for the selective binding of CDK4/6 ligands and protein degradation tags. This versatile reagent facilitates the construction of targeted protein degradation systems, enhancing the study of cellular pathways and therapeutic development related to CDK4/6 modulation. Its structural properties make it a valuable tool for researchers investigating protein homeostasis and targeted protein removal in various biological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2172820-07-2 |
| Applications | VHL-1 alkyl Linker |
| Formula | C28H38N4O7S |
| Molecular Weight | 574.69 |
| SMILES | O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCOCCC(O)=O)=O)=O)C[C@H](O)C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.