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VH032 analogue-1

Ligands for E3 Ligase

VH032 analogue-1 is an E3 ligase ligand that targets the von Hippel-Lindau (VHL) protein, facilitating its recruitment. This analogue serves as a key intermediate in the synthesis of PROTAC molecules by removing protective groups under acidic conditions. Its role in PROTAC synthesis makes it a valuable tool for researchers developing targeted protein degradation strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2111829-84-4
Applications	Ligands for E3 Ligase
Formula	C₂₃H₃₀N₄O₅S
Molecular Weight	474.57
SMILES	CC(N=CS1)=C1C(C=C2)=CC=C2CNC([C@H]3N(C[C@@H](C3)O)C(CNC(OC(C)(C)C)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.