VH032-C3-Boc is a Boc-modified derivative of VH032, functioning as a ligand for the E3 ligase von Hippel-Lindau (VHL). Under acidic conditions, VH032-C3-Boc enables the removal of the protective group, facilitating direct utilization in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound serves as an essential intermediate for developing VHL-based PROTACs, contributing to advancements in targeted protein degradation research.
VH032-C3-Boc is a Boc-modified derivative of VH032, functioning as a ligand for the E3 ligase von Hippel-Lindau (VHL). Under acidic conditions, VH032-C3-Boc enables the removal of the protective group, facilitating direct utilization in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound serves as an essential intermediate for developing VHL-based PROTACs, contributing to advancements in targeted protein degradation research.
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