VH032-C6-NH-Boc is a Boc-modified ligand that targets the von Hippel-Lindau (VHL) E3 ligase, facilitating the recruitment of VHL proteins. Under acidic conditions, it readily deprotection occurs, allowing its direct utilization in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound serves as a crucial intermediate in developing PROTACs utilizing VHL ligands, thereby advancing research in targeted protein degradation.
VH032-C6-NH-Boc is a Boc-modified ligand that targets the von Hippel-Lindau (VHL) E3 ligase, facilitating the recruitment of VHL proteins. Under acidic conditions, it readily deprotection occurs, allowing its direct utilization in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound serves as a crucial intermediate in developing PROTACs utilizing VHL ligands, thereby advancing research in targeted protein degradation.
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