VH032

Catalog No.: A80445
VHL Ligand
VH032 is a potent ligand for the von Hippel-Lindau (VHL) protein, acting primarily by inhibiting the interaction between VHL and hypoxia-inducible factor 1-alpha (HIF-1α). Its high affinity and specificity make VH032 an essential tool for research applications involving targeted protein degradation through PROTAC technology. This compound facilitates the study of VHL-mediated pathways and the regulation of hypoxic responses in various biological contexts.
Grouped product items
Size Price Stock Qty
1mg
$30.00
In stock
2mg
$45.00
In stock
5mg
$70.00
In stock
10mg
$125.00
In stock
25mg
$235.00
In stock
50mg
$335.00
In stock
100mg
$460.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionVH032 is a potent ligand for the von Hippel-Lindau (VHL) protein, acting primarily by inhibiting the interaction between VHL and hypoxia-inducible factor 1-alpha (HIF-1α). Its high affinity and specificity make VH032 an essential tool for research applications involving targeted protein degradation through PROTAC technology. This compound facilitates the study of VHL-mediated pathways and the regulation of hypoxic responses in various biological contexts.
Product Information
Catalog NumA80445
FormulaC24H32N4O4S
Molecular Weight472.60
CAS Number1448188-62-2
SMILESCC(N=CS1)=C1C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@H](C(C)(C)C)NC(C)=O)=O)=O)C=C2
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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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