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VHL-SF2

VHL Ligand

VHL-SF2 is a selective ligand for the von Hippel-Lindau (VHL) protein, facilitating the synthesis of PROTACs (proteolysis-targeting chimeras). By engaging the VHL E3 ubiquitin ligase, VHL-SF2 promotes the targeted degradation of specific proteins, making it a valuable tool in drug discovery and development. This compound is essential for researchers investigating targeted protein degradation and enhancing the therapeutic potential of protein-based treatments.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3050690-24-6
Applications	VHL Ligand
Formula	C₃₁H₃₉FN₄O₇S₂
Molecular Weight	662.79
SMILES	CC(C)[C@H](C1=CC(C)=NO1)C(N2[C@@H](C[C@H](C2)S(F)(=O)=O)C(N[C@H](C3=CC=C(C4=C(N=CS4)C)C=C3)CC(OC(C)(C)C)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.