Fig. 1 · Structure
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Vicenin 3
ACE Inhibitor
Vicenin 3 is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 46.91 μM, sourced from the aerial parts of Desmodium styracifolium. This compound has demonstrated the ability to mitigate interleukin-1 beta (IL-1β)-induced extracellular matrix degradation in SW1353 chondrocytes by modulating the MAPK signaling pathway. Vicenin 3 is relevant for research applications focusing on osteoarthritis (OA) and hypertension, providing insights into the mechanisms of these conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 59914-91-9 |
| Applications | ACE Inhibitor |
| Formula | C26H28O14 |
| Molecular Weight | 564.49 |
| SMILES | OC1=C([C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)CO)C(O)=C(C(C=C(C3=CC=C(O)C=C3)O4)=O)C4=C1[C@H]5[C@@H]([C@H]([C@H](O)CO5)O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.