Fig. 1 · Structure
Documents & Downloads
Vif-ElonginC interaction inhibitor 1
Vif Inhibitor
Vif-ElonginC Interaction Inhibitor 1 is an effective inhibitor targeting the interaction between HIV-1 Vif and ElonginC. This compound significantly restricts HIV-1 replication in Vif-nonpermissive cells by preventing Vif-mediated degradation of the restriction factors A3G, APOBEC3C, and APOBEC3F. Additionally, it enhances the incorporation of A3G into HIV-1 virions, thereby reducing viral infectivity. This compound serves as a valuable tool for research into HIV-1 biology and potential therapeutic interventions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 374679-27-3 |
| Applications | Vif Inhibitor |
| Formula | C29H21NO4 |
| Molecular Weight | 447.48 |
| SMILES | O=C(OCC)C1=C2C=C(C=CN2C(C(C3=CC=C4C=CC=CC4=C3)=O)=C1)C(C5=CC=CC=C5)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.