Vildagliptin-d3 is the deuterium-labeled analog of Vildagliptin, a highly selective dipeptidyl peptidase IV (DPP-IV) inhibitor that exhibits an IC50 of 3.5 nM in human Caco-2 cells. This stable isotope is ideal for tracer studies in metabolic research, particularly in exploring glucose metabolism and the pharmacokinetics of DPP-IV inhibitors. Vildagliptin-d3 offers exceptional oral bioavailability and retains significant antihyperglycemic activity, making it valuable in diabetes research applications.
Vildagliptin-d3 is the deuterium-labeled analog of Vildagliptin, a highly selective dipeptidyl peptidase IV (DPP-IV) inhibitor that exhibits an IC50 of 3.5 nM in human Caco-2 cells. This stable isotope is ideal for tracer studies in metabolic research, particularly in exploring glucose metabolism and the pharmacokinetics of DPP-IV inhibitors. Vildagliptin-d3 offers exceptional oral bioavailability and retains significant antihyperglycemic activity, making it valuable in diabetes research applications.
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