Vildagliptin-d7 is a deuterium-labeled derivative of Vildagliptin, a selective dipeptidyl peptidase IV (DPP-IV) inhibitor with notable potency, exhibiting an IC50 of 3.5 nM in human Caco-2 cells. This stable isotope can be utilized in studies focusing on pharmacokinetics and metabolic profiling of DPP-IV inhibitors, providing insight into their antihyperglycemic effects and oral bioavailability. Vildagliptin-d7 serves as a valuable tool for researchers investigating diabetes therapeutics and related metabolic disorders.
Vildagliptin-d7 is a deuterium-labeled derivative of Vildagliptin, a selective dipeptidyl peptidase IV (DPP-IV) inhibitor with notable potency, exhibiting an IC50 of 3.5 nM in human Caco-2 cells. This stable isotope can be utilized in studies focusing on pharmacokinetics and metabolic profiling of DPP-IV inhibitors, providing insight into their antihyperglycemic effects and oral bioavailability. Vildagliptin-d7 serves as a valuable tool for researchers investigating diabetes therapeutics and related metabolic disorders.
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