Fig. 1 · Structure
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Vincamine
Vasodilator
Vincamine is a monoterpenoid indole alkaloid that functions primarily as a peripheral vasodilator. It selectively regulates microcirculation in the brain, enhancing blood flow and oxygen delivery. Additionally, Vincamine acts as a GPR40 agonist, providing protective effects on pancreatic β-cells by enhancing glucose-stimulated insulin secretion and improving glucose homeostasis in vivo. Its unique properties make Vincamine valuable for research focused on type 2 diabetes mellitus (T2DM) and related metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1617-90-9 |
| Applications | Vasodilator |
| Formula | C21H26N2O3 |
| Molecular Weight | 354.44 |
| SMILES | O=C(OC)[C@@]1(O)C[C@@]2(CC)[C@@]3([H])C(N1C4=CC=CC=C54)=C5CCN3CCC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.