Fig. 1 · Structure
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Vincanol
Voltage-Gated Na+ Channel Inhibitor
Vincanol ((-)-Isoeburnamine) is a potent inhibitor of voltage-gated Na+ channels, demonstrating an IC50 value of 40 μM against sodium currents. Its mechanism of action reveals significant neuroprotective effects, making it valuable for research in neurological disorders. Investigators may utilize Vincanol to explore its potential therapeutic applications in conditions associated with excitotoxicity and neuronal injury.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 19877-89-5 |
| Applications | Voltage-Gated Na+ Channel Inhibitor |
| Formula | C19H24N2O |
| Molecular Weight | 296.41 |
| Synonyms | (-)-Isoeburnamine; (-)-epi-Eburnamine |
| SMILES | O[C@H]1N2C3=C(CCN4[C@]3([C@](CC)(C1)CCC4)[H])C5=C2C=CC=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.