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Vipadenant, also known as BIIB014, CEB-4520, is a potent, selective and orally available adenosine A2A receptor antagonist under development for Parkinson's disease. Vipadenant demonstrates strong oral activity in commonly used models of Parkinson's disease.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.12 mL | 155.6 mL | 311.19 mL |
| 0.5 mM | 6.22 mL | 31.12 mL | 62.24 mL |
| 1 mM | 3.11 mL | 15.56 mL | 31.12 mL |
| 5 mM | 0.62 mL | 3.11 mL | 6.22 mL |
*The above data is based on the productmolecular weight 321.344. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A13963 |
|---|---|
| Actions | Antagonist |
| M. Wt | 321.344 |
| Formula | C16H15N7O? |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 442908-10-3 |
| Synonyms | BIIB014, BIIB-014, BIIB 014, CEB-4520, CEB 4520, CEB4520, V-2006, V2006, V 2006, VER-11135, VER-A00-11, VER-A00049, VER-ADO-49, Vipadenant |
| SMILES | NC1=NC(C2=CC=CO2)=C(N=NN3CC4=CC=C(N)C(C)=C4)C3=N1 |
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