Fig. 1 · Structure

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Vitexicarpin

Cat. No. A12134 CAS 479-91-4
Vitexicarpin, a flavonoid from the fruits of Vitex rotundifolia, inhibits mouse lymphocyte proliferation and growth of cell lines in vitro.

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Biological Activity

Cellular Effect

Cell Line Activity Value Description Reference
HCT-116 GI50 119 ng/mL Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay [PMID: 11975496]
KB IC50 97 nM Cytotoxicity against human KB cells after 72 hrs by MTS assay [PMID: 20356063]
PC-12 GI50 114 ng/mL Cytotoxicity against rat PC12 cells assessed as growth inhibition after 72 hrs by MTT assay [PMID: 11975496]
RAW264.7 IC50 21.4 μM Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess method [PMID: 24035341]

Specifications

Manufacturer Adooq Bioscience
CAS Number 479-91-4
Formula C19H18O8
Molecular Weight 374.34
Synonyms Casticin
SMILES
COC1=C(C=C(C=C1)C2=C(C(=O)C3=C(C(=C(C=C3O2)OC)OC)O)OC)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

SolventReported Solubility
DMSO 67 mg/mL (178.98 mM)

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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