Fig. 1 · Structure
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VK-II-86
Carvedilol Analogue
VK-II-86 is a carvedilol analogue that exhibits unique properties by lacking β-adrenoceptor antagonist activity. This compound effectively prevents hypokalaemia-induced ventricular arrhythmias through its multi-channel modulation and protects against alterations in ion channel activity as well as oxidative stress. VK-II-86 is valuable for research applications related to cardiac arrhythmias and ion channel regulation in the context of hypokalaemia.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 955371-84-3 |
| Applications | Carvedilol Analogue |
| Formula | C25H28N2O4 |
| Molecular Weight | 420.50 |
| SMILES | OC(CCOC1=CC=CC(N2)=C1C3=C2C=CC=C3)CNCCOC4=CC=CC=C4OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.