Fig. 1 · Structure

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VKT-17-P4-23

DksA Inhibitor

VKT-17-P4-23 is a DksA inhibitor designed to penetrate the blood-brain barrier. DksA, a conserved transcriptional regulator in Gram-negative bacteria, has a Kd of 124 μM. This compound demonstrates antibacterial activity against both planktonic and intracellular pathogens, particularly Salmonella, and is effective against persistent bacterial infections. VKT-17-P4-23 is suitable for research involving Salmonella infection and the DksA-regulated SPI-2-dependent survival pathway.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2411865-57-9
Applications DksA Inhibitor
Formula C13H16N4O
Molecular Weight 244.29
SMILES
O=C(C1=NNC=N1)NCCCCC2=CC=CC=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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