VMAPRTLFL is a 9-mer peptide that acts as a ligand for HLA-E, derived from the signal peptide of HLA-G. This peptide is essential for modulating the activity of adaptive natural killer (NK) cells, enhancing their proliferation, antibody-dependent cellular cytotoxicity (ADCC), and interferon-gamma (IFN-γ) release through upregulation of CD25 expression. VMAPRTLFL is valuable for research into human cytomegalovirus (HCMV) infection, transplant rejection, and mechanisms underlying pregnancy immunity.
VMAPRTLFL is a 9-mer peptide that acts as a ligand for HLA-E, derived from the signal peptide of HLA-G. This peptide is essential for modulating the activity of adaptive natural killer (NK) cells, enhancing their proliferation, antibody-dependent cellular cytotoxicity (ADCC), and interferon-gamma (IFN-γ) release through upregulation of CD25 expression. VMAPRTLFL is valuable for research into human cytomegalovirus (HCMV) infection, transplant rejection, and mechanisms underlying pregnancy immunity.
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