Fig. 1 · Structure

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VNI

Cat. No. A52903 CAS 1246770-52-4

CYP51 Inhibitor

VNI is a potent inhibitor of cytochrome P450 51 (CYP51), targeting sterol synthesis in the parasite Trypanosoma cruzi. Its mechanism of action disrupts the biosynthesis of essential sterols, leading to impaired growth and viability of the pathogen. VNI is primarily utilized in research focused on anti-parasitic strategies and the development of therapeutics for Chagas disease.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1246770-52-4
Applications CYP51 Inhibitor
Formula C26H19Cl2N5O2
Molecular Weight 504.37
SMILES
O=C(N[C@H](C1=CC=C(Cl)C=C1Cl)CN2C=CN=C2)C3=CC=C(C4=NN=C(C5=CC=CC=C5)O4)C=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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