Fig. 1 · Structure
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Vobramitamab duocarmazine
Anti-B7-H3 ADC
Vobramitamab duocarmazine is a humanized antibody-drug conjugate (ADC) targeting B7-H3 (CD276). This compound features a cleavable linker-Duocarmycin payload, Vc-seco-DUBA, covalently linked to an anti-B7-H3 humanized IgG1κ monoclonal antibody. It exhibits significant antineoplastic activity, making it a valuable reagent for cancer research focused on tumor immunology and therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2490556-51-7 |
| Applications | Anti-B7-H3 ADC |
| Synonyms | AEX4089DC1; MGC018 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.