Vorapaxar sulfate is a selective antagonist of protease-activated receptor-1 (PAR-1), demonstrating competitive inhibition with a Ki value of 8.1 nM. This antiplatelet agent effectively inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner. Vorapaxar sulfate is utilized in research focused on thrombotic disorders and cardiovascular diseases, providing insights into platelet activation and aggregation pathways.
Vorapaxar sulfate is a selective antagonist of protease-activated receptor-1 (PAR-1), demonstrating competitive inhibition with a Ki value of 8.1 nM. This antiplatelet agent effectively inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner. Vorapaxar sulfate is utilized in research focused on thrombotic disorders and cardiovascular diseases, providing insights into platelet activation and aggregation pathways.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
