Vorasidenib

Catalog No.: A16908

IDH1 Inhibitor

Vorasidenib

Vorasidenib Chemical Structure

CAS NO. 1644545-52-7

Vorasidenib, also known as AG-881, is a potent and selective orally available inhibitor of mutated forms of both isocitrate dehydrogenase type 1 (IDH1, IDH1 [NADP+] soluble) in the cytoplasm and type 2 (IDH2, isocitrate dehydrogenase [NADP+], mitochondrial) in the mitochondria, with potential antineoplastic activity.

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Package Price Qty
2 mg
$85.00
5 mg
$135.00
10 mg
$225.00
50 mg
$675.00
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Biological Activity

Vorasidenib, also known as AG-881, is a potent and selective orally available inhibitor of mutated forms of both isocitrate dehydrogenase type 1 (IDH1, IDH1 [NADP+] soluble) in the cytoplasm and type 2 (IDH2, isocitrate dehydrogenase [NADP+], mitochondrial) in the mitochondria, with potential antineoplastic activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.11 mL 120.56 mL 241.11 mL
0.5 mM 4.82 mL 24.11 mL 48.22 mL
1 mM 2.41 mL 12.06 mL 24.11 mL
5 mM 0.48 mL 2.41 mL 4.82 mL

*The above data is based on the productmolecular weight 414.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16908
Actions Inhibitor
M. Wt 414.74
Formula C14H13ClF6N6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1644545-52-7
Synonyms AG-881, AG 881, AG881
SMILES C[[email protected]@H](NC1=NC(C2=NC(Cl)=CC=C2)=NC(N[[email protected]](C)C(F)(F)F)=N1)C(F)(F)F

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