Catalog No.: A19394

VEGFR/PDGFR inhibitor


Vorolanib Chemical Structure

CAS NO. 1013920-15-4

Vorolanib (CM082; X-82) is an orally active, multikinase VEGFR/PDGFR inhibitor.

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Biological Activity

Vorolanib (CM082; X-82) is an orally active, multikinase VEGFR/PDGFR inhibitor.
In vitro DMSO 82 mg/mL (186.61 mM)
Water <1 mg/mL
Ethanol 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.75 mL 113.77 mL 227.54 mL
0.5 mM 4.55 mL 22.75 mL 45.51 mL
1 mM 2.28 mL 11.38 mL 22.75 mL
5 mM 0.46 mL 2.28 mL 4.55 mL

*The above data is based on the productmolecular weight 439.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A19394
Actions Inhibitor
CAS No. 1013920-15-4
Formula C23H26FN5O3
M. Wt 439.48
Solubility DMSO
Purity >98%
Synonyms CM082; X-82
SMILES O=C1/C(C2=CC(F)=CC=C2N1)=C/C(NC(C)=C3C(N[[email protected]@H]4CN(C(N(C)C)=O)CC4)=O)=C3C

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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