Fig. 1 · Structure
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Vorozole (R83842)
Aromatase Inhibitor
Vorozole is a potent and selective non-steroidal aromatase inhibitor, designed for oral administration. It demonstrates significant antitumor activity in vivo, making it a valuable tool for researchers studying mammary cancer and related hormonal pathways. This compound is instrumental in the exploration of the therapeutic potential for estrogen-dependent tumors.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 129731-10-8 |
| Applications | Aromatase Inhibitor |
| Formula | C16H13ClN6 |
| Molecular Weight | 324.77 |
| Synonyms | (+)-Vorozole; R83842 |
| SMILES | CN1N=NC2=CC=C([C@H](C3=CC=C(Cl)C=C3)N4N=CN=C4)C=C21 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.