Fig. 1 · Structure
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(-)-Vorozole
Cytochrome P450 Inhibitor
(-)-Vorozole is a selective inhibitor of cytochrome P450, specifically targeting aromatase. This non-steroidal compound exhibits significant antitumor activity in vivo and is primarily utilized in breast cancer research. Its potent inhibitory properties make it a valuable tool for investigating estrogen synthesis and its implications in various malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 132042-69-4 |
| Applications | Cytochrome P450 Inhibitor |
| Formula | C16H13ClN6 |
| Molecular Weight | 324.77 |
| SMILES | CN1N=NC2=CC=C(C=C21)[C@H](N3C=NC=N3)C4=CC=C(C=C4)Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.