Fig. 1 · Structure
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Votoplam hydrochloride
HTT Regulator
Votoplam hydrochloride is an HTT gene regulator with an IC50 of ≤ 0.1 μM. This compound plays a critical role in modulating HTT expression and is primarily utilized in research focused on Huntington's disease. Its efficacy in regulating the gene associated with this neurodegenerative disorder provides valuable insights for therapeutic development and investigation of disease mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2407851-28-7 |
| Applications | HTT Regulator |
| Formula | C21H26ClN9O |
| Molecular Weight | 455.94 |
| Synonyms | PTC518 hydrochloride |
| SMILES | OC1=C(C2=NN=C3C(N=NN3C4CC(C)(C)NC(C)(C4)C)=C2)C=CC(N5N=CC=N5)=C1.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.