Voxelotor

Catalog No.: A20863

HbS polymerization inhibitor

Voxelotor

Voxelotor Chemical Structure

CAS NO. 1446321-46-5

Voxelotor (GBT 440) is an orally bioavailable sickle hemoglobin (HbS) polymerization inhibitor.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$155.00
50 mg
$460.00
100 mg
$920.00
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Biological Activity

Voxelotor (GBT 440) is an orally bioavailable sickle hemoglobin (HbS) polymerization inhibitor.
In vitro DMSO 60 mg/mL (177.84 mM)
Water Insoluble
Ethanol 60 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.64 mL 148.21 mL 296.41 mL
0.5 mM 5.93 mL 29.64 mL 59.28 mL
1 mM 2.96 mL 14.82 mL 29.64 mL
5 mM 0.59 mL 2.96 mL 5.93 mL

*The above data is based on the productmolecular weight 337.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20863
Actions Inhibitor
CAS No. 1446321-46-5
Formula C19H19N3O3
M. Wt 337.37
Purity >98%
Synonyms GBT 440, GBT-440, GBT440
SMILES OC1=CC=CC(OCC2=C(C3=CC=NN3C(C)C)N=CC=C2)=C1C=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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