Catalog No.: A20863
HbS polymerization inhibitor
Voxelotor (GBT 440) is an orally bioavailable sickle hemoglobin (HbS) polymerization inhibitor.
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Voxelotor 5mg
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Voxelotor 10mg
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Voxelotor 50mg
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Voxelotor 100mg
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Voxelotor (GBT 440) is an orally bioavailable sickle hemoglobin (HbS) polymerization inhibitor.
Chemical Information
Catalog Num A20863
Formula C19H19N3O3
Molecular Weight 337.37
CAS Number 1446321-46-5
Synonyms GBT 440, GBT-440, GBT440

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro DMSO 60 mg/mL (177.84 mM)
Water Insoluble
Ethanol 60 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.64 mL 148.21 mL 296.41 mL
0.5 mM 5.93 mL 29.64 mL 59.28 mL
1 mM 2.96 mL 14.82 mL 29.64 mL
5 mM 0.59 mL 2.96 mL 5.93 mL
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