Signaling Pathway
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| Discription | Voxelotor (GBT 440) is an orally bioavailable sickle hemoglobin (HbS) polymerization inhibitor. |
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| Catalog Num | A20863 |
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| Formula | C19H19N3O3 |
| Molecular Weight | 337.37 |
| CAS Number | 1446321-46-5 |
| SMILES | OC1=CC=CC(OCC2=C(C3=CC=NN3C(C)C)N=CC=C2)=C1C=O |
| Synonyms | GBT 440, GBT-440, GBT440 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 60 mg/mL (177.84 mM) | |
| Water | Insoluble | ||
| Ethanol | 60 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.64 mL | 148.21 mL | 296.41 mL |
| 0.5 mM | 5.93 mL | 29.64 mL | 59.28 mL |
| 1 mM | 2.96 mL | 14.82 mL | 29.64 mL |
| 5 mM | 0.59 mL | 2.96 mL | 5.93 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
