Fig. 1 · Structure
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VPC-70063
Myc-Max Inhibitor
VPC-70063 is a selective Myc-Max inhibitor that effectively disrupts Myc-Max transcriptional activity with an IC50 of 8.9 μM. This compound has been shown to reduce UBE2C promoter activity and AR-V7 levels while inducing PARP cleavage, contributing to its pro-apoptotic effects. VPC-70063 serves as a valuable tool for investigating the mechanisms of cancer progression and potential therapeutic strategies targeting the Myc-Max interaction.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 13571-44-3 |
| Applications | Myc-Max Inhibitor |
| Formula | C16H12F6N2S |
| Molecular Weight | 378.34 |
| SMILES | FC(F)(C1=CC(NC(NCC2=CC=CC=C2)=S)=CC(C(F)(F)F)=C1)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.