Fig. 1 · Structure
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VPC-80051
hnRNPA1 Splicing Activity Inhibitor
VPC-80051 is an hnRNP A1 splicing activity inhibitor that directly interacts with the RNA-binding domain of hnRNP A1. This compound effectively reduces AR-V7 mRNA levels in the 22Rv1 castration-resistant prostate cancer cell line. VPC-80051 is a valuable tool for investigating the role of splicing factors in prostate cancer research and therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2410979-04-1 |
| Applications | hnRNPA1 Splicing Activity Inhibitor |
| Formula | C16H13F2N3O |
| Molecular Weight | 301.29 |
| SMILES | C[C@@H](C1=CC(F)=C(C=C1)F)NC(C2=C3C(C=CC=C3)=NN2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.