Biological Activity
Vps34-IN-2 is a novel, potent and selective inhibitor of Vps34 with IC50s of 2 and 82 nM on the Vps34 enzymatic assay and the GFP-FYVE cellular assay, respectively.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.85 mL | 124.25 mL | 248.5 mL |
0.5 mM | 4.97 mL | 24.85 mL | 49.7 mL |
1 mM | 2.49 mL | 12.43 mL | 24.85 mL |
5 mM | 0.5 mL | 2.49 mL | 4.97 mL |
*The above data is based on the productmolecular weight 402.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A16933 |
---|---|
Actions | Inhibitor |
CAS No. | 1523404-29-6 |
Formula | C18H25F3N4O3 |
M. Wt | 402.41 |
Solubility | DMSO |
Purity | >98% |
SMILES | O=C1C=C(N2[[email protected]](C)COCC2)N=C3N(CC(C(C)C)=O)[[email protected]](C(F)(F)F)CCN31 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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